Adult cancer survivors can take part in study
(Aug. 10, 2009) We are conducting a research study to find out about how cancer survivors receive their follow up care, and clinical experiences with Cancer Survivorship Care Plans, especially in rural areas of the state. We invite you to participate in a focus group to share your experiences and thoughts.
Who is eligible:
--Age 50-80
--Any previous diagnosis and treatment for cancer in the previous 10 years, excluding non-melanoma skin cancers
--We are intentionally interested in patients who receive care in non-metro areas of the state
What’s involved
--We invite you to join in a 1-2 hour group discussion at a centralized location
--Come share your thoughts and experiences and provide valuable feedback
--No lab or other testing is required
--This is not a clinic, and no treatment will be provided
Financial compensation will be provided.
Please contact Linda Overholser, MD (Principal Investigator) if you would like to participate (720) 848-9534, or linda.overholser@ucdenver.edu. COMIRB Protocol # 08-0241. PI: Linda S. Overholser, MD
Healthy people: rheumatoid arthritis study
(July 27, 2009) Healthy subjects are needed for a research study: “The role of Complement in the Pathogenesis of Rheumatoid Arthritis in Healthy Subjects.”
Criteria
• 22-65 years old
• Non Smoking
• Not diagnosed with rheumatoid arthritis
You will be asked to donate 20-mL of blood via veinipuncture. The entire procedure will take about 30 minutes of your time. You will be compensated for your time; however no parking fees will be paid.
Anyone interested can contact Brandt Levitt, Division of Rheumatology, UC-Denver, 303-724-7599 or Brandt.Levitt@UCHSC.edu.
Principal investigator: Nirmal K. Banda, PhD, associate professor; COMIRB No. 08-1041
People sought for study on cause of lupus
(July 6, 2009) Healthy volunteers between the ages of 18 - 60 are needed to participate in a research study investigating the cause of lupus in the "Functional Analysis of Complement Receptor 2 as a Lupus Susceptibility Gene" study. Volunteers will be asked to donate blood for immunological studies.
Eligibility is limited to individuals who are in good health, who do not smoke, and who are not taking medications. Compensation for participation will be provided. If interested please contact Carissa Homme at 303-724-7522 or by email at carissa.homme@ucdenver.edu. PI: Susan A. Boackle, MD. COMIRB #06-0501
Evaluating female hormonal changes*
(June 9, 2009) The University of Colorado Denver is looking for healthy women age 18 and up to participate in a study. The research will evaluate whether female hormonal changes during the menstrual cycle change the amount of receptors for HIV on cells.
Volunteers:
• Healthy women who do not have HIV
• Ages 18 and up
• Regular menstrual cycle
• Not pregnant
• Not on hormonal contraceptives
Measurement and study procedures include:
• 4 visits over 2 months
• 3 of the visits within the same month.
• Testing for sexually transmitted diseases including HIV testing.
Compensation will be provided. Contact: Kelsey Melander 303-724-3066, kelsey.melander@ucdenver.edu. COMIRB No. 06-0529. PI: Amie Meditz, MD.
*Originally posted 4/15/09
Healthy people needed for amino acid study
(May 27, 2009) We are looking for volunteers to participate in a study investigating the effects of an amino acid (a building block of a protein) on the production of protective proteins that are made by human cells & tissues in response to stress and injury.
● Male or female, 18-45
● Not taking any medications except for Birth control pills and Synthyroid
● Non-smoker
● No chronic illness
● Compensation provided
Volunteers will complete Visit 1 which consists of a physical exam and medical history. At that time if you qualify, an appointment will be made for Visit 2 which consists of one intravenous dose of either study drug or placebo for a total of 4 hours, emersion in a hot tub for 2 hours, and collection of blood samples over 30 hours so you will need to stay overnight in the Clinical Translation Research Center (CTRC). Visit 3(at least 2 weeks after visit 2) will be your last visit which will require one intravenous dose of study drug or placebo, emersion in a hot tub for 2 hours, and collection of blood samples over 30 hours again requiring you to spend the night at the CTRC. The Clinical Translation Research Center is located at the University Hospital on the 12th floor.
If you interested please call Rebecca Safon at 720-848-6752 or email at Rebecca.safon@ucdenver.edu. COMIRB No. 06-0652 P.I.: Paul Wischmeyer, MD, Department of Anesthesiology.
Insomnia after breast cancer treatment
(May 13, 2009) The purpose of the study is to understand insomnia in women after treatment for breast cancer and compare the effects of a previously tested behavioral approach to improve sleep with a behavioral approach that has not been tested.
If you agree to participate, you will be in the study for up to six months. (You will be asked to fill out brief surveys at 3- and 6-months.)
Who is eligible to participate?
• Women, age 21-65
• 1-36 months after completion of radiation or chemotherapy for breast cancer
• Symptoms of chronic insomnia that started at the time of breast cancer diagnosis or got worse
• Speak and write English
What will you have to do?
• Carefully read and sign consent form • Participate in initial interview and six weekly, individual sessions to improve insomnia. These sessions will be conducted in person and by phone and will last 15-30 min. • Complete “paper and pencil” surveys before the start of the sessions, at the end of the sessions, and at three and six months after the sessions • Keep a daily sleep diary during the six week sessions • Wear a wristwatch (actigraphy watch) that measures body movement during the six week sessions.
Compensation provided. Information: Dr. Ellyn Matthews. Office: (303) 724-8552, cell: (303) 522-0981, ellyn.matthews@ucdenver.edu. COMIRB #07-0924
People wanted for Type 2 diabetes study
(April 30, 2009) We are interested in young people and adults who were diagnosed with type 2 diabetes when they were less than 18 years of age. Type 2 diabetes is usually a problem only for adults, but now it is seen in kids and teenagers. We are working to learn the best ways to take care of diabetes in youth.
The study requires a small (27mL) blood draw and an interview about the patient’s family and medical history. The visit will take about an hour. You will be compensated for your time.
Enrollment criteria:
Participants must have received a diagnosis of Type 2 Diabetes when they were less than 18 years of age and meet the following criteria:
• Diagnosis of type 2 diabetes by ADA criteria
• Patients under 18 must have a family member or guardian willing to be involved in the consent process.
• Women cannot be pregnant.
If you are interested in the study contact Amber Hull at The Children’s Hospital to schedule an appointment. COMIRB No. 08-0400.
Macrovascular disease in adolescents with type 1 diabetes
(April 15, 2009) Participants are sought for a study to assess risk for cardiovascular disease in adolescents with and with out type 1 diabetes.
Eligibility criteria:
• Adolescents with type 1 diabetes between the ages of 12-19 years for at least 5 years and no other serious medical problems.
• Adolescents without diabetes between the ages of 12-19 who have no serious medical problems.
Subjects who participate in the study will receive compensation for the blood draw after an overnight fast, urine collection, vital signs, and measurements.
For further information contact Franziska Bishop at 303-724-6764 or e-mail, franziska.bishop@ucdenver.edu. Paul Wadwa, MD, Principal Investigator. COMIRB Protocol 07-0780.
Exercise metabolism, diabetes research study
(March 10, 2009) Men and women with Type II diabetes aged 30-50 are encouraged to participate in a metabolism study investigating how fat stored in your muscle affects insulin activity.
You cannot participate if you:
• smoke
• have hyperlipidemia
• or have been told by your doctor not to exercise
You must be diagnosed with type II diabetes less than 10 years ago.
Two different preliminary assessments will measure:
• Body fat content
• Maximal exercise capacity (VO2max)
• Heart rhythm
• Resting metabolic rate
• Glucose tolerance
• Blood tests
• Health and physical examination performed by a physician.
Volunteers will complete one metabolic study day following a 12-hour fast, where you will lie quietly for 4 hours, exercise for 1.5 hours at an easy to moderate intensity (45 percent of maximal capacity), and lie quietly again after exercise for 2 hours. All 3 visits will be performed at the General Clinical Research Center. Diet will be controlled for three days before each study day.
For the metabolic study day, the following will occur:
• Infusion of naturally occurring tracer of carbohydrate and fat through an intravenous catheter
• Blood sampling from a catheter placed in a hand vein
• 3 muscle biopsies
• 1.5 hours of exercise at 45 percent of maximal capacity
Compensation will be provided. P.I. Dr. Bryan Bergman, COMIRB No. 03-398. Call Devon at 303-724-3968 for more information about this study.
Volunteers with cardiovascular conditions needed
(Feb. 11, 2009) People with a cardiovascular condition are needed to help train budding MDs. Volunteers are asked to allow a small group of students interview them 10:15 a.m.–noon Wednesday, April 15. As part of their education, our first-year medical students need to learn about the problems people with cardiovascular illness experience. If you volunteer, students will interview you as if you were their patient in a private, informal, and comfortable environment. You can come with your significant other or caretaker. There is nothing to prepare ahead of time.
All interviews are at the Anschutz Medical Center Campus, located at E. Colfax Avenue and Peoria Street in Aurora, Colo. Specific information as to free parking and location will be sent to each participant. Participants will receive a $25 gift certificate.
If you are interested, contact Sharon Campbell, Medical Student Course Coordinator, at 303-724-7400 or Sharon.Campbell@ucdenver.edu.
Investigating the cause of lupus
(Jan. 26, 2009) We are looking for healthy volunteers between the ages of 18 - 60 to participate in a research study investigating the cause of lupus. Volunteers will be asked to donate blood for immunological studies. Eligibility is limited to individuals who are in good health, who do not smoke, and who are not taking medications.
Compensation for participation will be provided. If interested please contact Carissa Homme at 303-724-7522 or by e-mail at carissa.homme@ucdenver.edu. COMIRB No. 06-0501. PI: Susan A. Boackle, MD
Women needed for heart study
(Jan. 15, 2009) Healthy Women are needed for a cardiovascular research study to investigate what causes arteries to become unhealthy with menopause and the loss of estrogen. Qualifications:
- Pre-menopausal women 18-40 years and postmenopausal women between the age of 50-65 years
- Non-smokers Volunteers should NOT currently be taking birth control or hormone replacement therapy (HRT) or exercising vigorously more than two days a week.
Benefits for study volunteers include:
- Ultrasound of the blood vessels and heart
- Blood cholesterol profile
- Comprehensive dietary analyses
- Measurements of bone mineral density and body composition
- Compensation for your time
If you are interested in participating contact Lauren Tobin at 720-48-7561 or Lauren.Tobin@uchsc.edu. COMIRB No. 07-1097. Principle investigator: Kerrie Moreau, PhD
Help end PKD for 12.5 million worldwide
(Jan. 5, 2009) The University of Colorado Denver is currently enrolling for two studies of Polycystic Kidney Disease (PKD). Both studies are funded by the National Institutes of Health (NIH) and there is no cost for participation. Travel to Denver is provided at no cost to participants. In addition, blood pressure medicine, study medicine and home blood pressure monitors are provided free of charge to participants.
1. HALT PKD Study: We are enrolling adults who have PKD, up to age 64. This study is designed to investigate whether a combination of specific blood pressure medications, combined with controlling blood pressure to certain targeted levels, will slow the rate of kidney growth in PKD.
2. PKD Study of Children and Young Adults: We are also enrolling children and young adults between the ages of 8 and 21 years who have PKD. Travel is provided for the child and one parent at no cost. We are using 2 medications which are currently on the market. The study is being conducted to determine if the combination of these medicines is particularly effective in slowing growth of kidney cysts in young people with PKD. The medicines are pravastatin and lisinopril. Pravastatin has been used in patients with high cholesterol levels, while lisinopril is commonly used to treat high blood pressure. However, your child does not have to have high blood pressure or high cholesterol to participate in this study. The study is taking place at The Children’s Hospital in Denver.
Eligibility criteria include otherwise healthy children and young adults with PKD who are between 8 and 21 years old and who have normal kidney function. The study will involve three hospital visits over a four-year period. Each hospital visit will last two days and will involve blood pressure measurement, blood and urine testing, and radiology (x-ray) studies. Between hospital visits, participants will be asked to take medications and to record blood pressure measurements at home on a regular basis.
Information: PKD Research Group, University of Colorado Denver, Toll-Free: 877-765-9297 or PKD.Nurse@UCD.edu
Ranolazine and oxygen in leg muscles
(Dec. 12, 2008) Volunteers are needed for a study is examining whether the drug Ranolazine can improve the ability of leg muscles to utilize oxygen during exercise in people suffering from peripheral arterial disease. Eligible participants must be greater than 40 years of age and cannot have diabetes. For more information, contact Traci A. Kimball, MD (co-investigator and research coordinator) at 303-860-9900, ext 109. Principle Investigator: Mark R. Nehler MD; COMIRB #07-0257.
Altitude sickness research
(Nov. 13, 2008) The Altitude Research Center at the University of Colorado is recruiting subjects for a research study of Cerebrospinal Fluid Pressure and Acute Mountain Sickness. Subjects who have a history of altitude sickness (headache at high altitude) are encouraged to volunteer.
The study involves:
- screening visit (physical exam, blood draw and VO2 max test)
- a 10-hour day in a chamber that simulates high altitude
- exercise in the chamber (stationary bike)
- spinal catheter placed in lower back
- I.V. catheter placed in one arm
- several blood draws
- taking medication for altitude illness
Subjects must be healthy, non-pregnant, non-smoking men and women, 18-40 years of age. Qualified participants will receive monetary compensation.
For more information, call 303-724-1674 or e-mail altituderesearch@gmail.com. Principal investigator: Robert Roach, PhD; COMIRB #07-0810
Effects of asthma medication on lung test
(Nov. 11, 2008) Researchers are studying the effects of varying doses of mometasone furoate (AsmanexÒ) on a lung test called exhaled nitric oxide (eNO).
To qualify, participants must:
- be 18-65 years of age with mild to moderate asthma
- have no other respiratory diseases
Study participation involves:
- multiple visits to research unit over a seven-month period
- asthma tests and study medication at no cost
- withholding of participants’ current asthma medication
- financial compensation for qualified participants
Principal Investigator: Rohit Katial, MD; study #HS 2253. For more information call 303-398-1911 or e-mail wcru@njc.org.
Methamphetamine cessation study
(Nov. 3, 2008) Do you, or does someone you know have a problem with methamphetamine and want to quit? We are looking for volunteers for a placebo controlled research study to determine if a medication may help reduce or eliminate methamphetamine use. You will receive assessments including a physical examination, blood work, ECG and psycho-therapy at no cost. You will also receive compensation for your time. For further information, call 720-854-4200. All information is strictly confidential. Principal Investigator: Dr. Thomas P. Beresford. COMIRB # 07-0123
Study on rating pictures of food
(Oct. 30, 2008) Researchers are looking for men and women 20-60 years of age to participate in a research study on rating pictures of food.
- Participation will require a 90-minute session consisting of:
- drinking a small amount of a liquid supplement
- rating images of food on a computer
- completing questionnaires
Compensation will be provided for participation. For more information, contact Kyle Burger at 303-724-2926 or kyle.burger@ucdenver.edu. Principal Investigator: Marc Cornier, MD; COMIRB # 07-0497
Schizophrenia and smoking
(Oct. 30, 2008) Subjects are needed for a research study to test the safety and effectiveness of an investigational smoking cessation product (Varenicline Tartrate).
Participants should:
• be 18-75 years of age
• have been diagnosed with schizophrenia or schizoaffective disorder
• be in general good health
• be a current smoker who is trying to quit
• not currently be taking Bupropion or Chantix/Champix
Eligible participants will receive study-related medical care, lab work and examinations at no charge. For more information, contact Karen Devine at 303-724-3715. Primary Investigator: Chad D. Morris, PhD; COMIRB # 08-0291
Alternative medicine for urological symptoms
(Oct. 21, 2008) Researchers are seeking participants for the Complementary and Alternative Medicine for Urological Symptoms (CAMUS) study to determine whether Saw Palmetto (Serenoa repens) reduces unpleasant urinary symptoms caused by a type of enlarged prostate known as benign prostatic hyperplasia or BPH. These urinary symptoms can include a slow, interrupted or weak urinary stream, urgency, leaking or more frequent urination, especially at night.
Eligible participants must:
- be at least 45 years of age
- not have had surgery for an enlarged prostate
- not have another cause for urinary symptoms (such as prostate or bladder cancer, urinary tract disease or neurological problems)
- have a prostate specific antigen (PSA) level of less than 10 ng/ml
- be able to complete the study in the opinion of the investigator
Qualified participants will receive Saw Palmetto or placebo at no cost. All clinic visits, procedures and lab tests will be covered by the grant except for two physician visits (the initial visit and a visit at 72 weeks). Both of these visits are considered routine care for treating men with enlarged prostates and will, therefore, be billed to the patient or the patient’s insurance company.
Involvement in this study will be approximately 1.5 years. For more information, e-mail spencer.green@uchsc.edu or patricia.devore@uchsc.edu or call 720-848-1387. Principal Investigator: E. David Crawford, MD; COMIRB # 07-0183
Liver disease research study
(Oct. 3, 2008) We are looking for volunteers with and without liver disease, aged 18 or older who do not have HIV, to donate up to two units of blood at up to two visits.
These blood samples will be collected and stored to establish a blood bank for research testing in hopes of improving treatment and outcomes for future patients with liver disease.
African American volunteers are especially needed for this study.
If you are interested in participating in this research, please contact Megan Brocato at 303-724-1876 or megan.brocato@uchsc.edu. Participants will be compensated. Principal Investigator: Hugo Rosen, MD. COMIRB# 08-0364,