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Weight, diet and exercise 

 

Healthy overweight volunteers for weight-loss study on insulin metabolism

(Aug. 21, 2009) Needed: healthy, overweight male or female, ages 20-45, with a body mass index of 30-39 kg/m2 (http://www.nhlbisupport.com/bmi/bmi-m.htm) for a research study on the effect of weight loss on metabolism. Volunteers must be able to easily access the Anschutz Medical Campus for daily food pick-up for 11 weeks.

Research visits include:
2 morning screening appointments
3 overnight stays on the CTRC research unit at University Hospital 
Study procedures include IV testing with infusion of glucose and insulin, a muscle biopsy from the thigh area of the leg, and an MRI of the lower leg muscle. 

Compensation will be provided upon completion of the study. 

(PI:  Boris Draznin, MD, PhD; COMIRB #07-1203). Approved 3/31/09

This is updated from the early notice dated 7/1/09 - same study, same contact info.

People who have always been thin and those who struggle with weight sought for study

(July 15, 2009) Volunteers needed for an MRI research study looking at the brain’s response to over and under-eating.

The Effects of Energy Imbalance on Food Intake Behaviors

Contact us if you are:

  1. 25-35 years old
  2. Right handed and have no metal in your body
  3. Have no immediate family members who are overweight
  4. Body Mass Index is between 17-23 (check it out at http://nhlbisupport.com/bmi/)

Or

  1. Have at least one immediate family member who is overweight
  2. Body Mass Index is between 20-29 (check it out at http://nhlbisupport.com/bmi/)

Receive at no cost:

  1. Lab work
  2. Body fat measurement
  3. Brain imaging

Receive monetary compensation for your time.

COMIRB 05-0067. Principal Investigator: Marc-Andre Cornier, MD. Please Contact: Marc.Cornier@ucdenver.edu or 303-315-9115.

Sedentary subjects needed for an exercise metabolism research study

(April 2, 2009) Sedentary man or woman aged 30-50 can participate in a metabolism study investigating how fat stored in your muscle affects insulin activity.

Exclusions: You cannot participate if you: smoke, have hyperlipidemia, or have been told by your doctor not to exercise.

Two different preliminary assessments will measure:

Ø     Body fat content

Ø     Maximal exercise capacity (VO2max)

Ø     Heart rhythm

Ø     Resting metabolic rate

Ø     Glucose tolerance

Ø     Blood tests

Ø     Health and physical examination performed by a physician

Volunteers will complete one metabolic study day following a 12 hour fast, where you will lie quietly for 4 hours, exercise for 1.5 hours at an easy to moderate intensity (45 percent of maximal capacity), and lie quietly again after exercise for 2 hours. All 3 visits will be performed at the General Clinical Research Center. Diet will be controlled for 3 days before each study day.

For the metabolic study day, the following will occur:

Ø     Infusion of naturally occurring tracer of carbohydrate and fat through an    intravenous catheter

Ø     Blood sampling from a catheter placed in a hand vein

Ø     3 muscle biopsies

Ø     1.5 hours of exercise at 45 percent of maximal capacity

Compensation will be provided. P.I. Dr. Bryan Bergman, COMIRB # 03-398. Call Devon at 303-724-3968 for more information.

Dietary restriction, fasting study for obese men

(March 3, 2009) Men wanting to lose weight can take part in the Dietary Restriction vs. Intermittent Fasting study at UC Denver to compare two different diet methods: a low-calorie diet or an every other day fast.

Participants must be

• Obese men between the ages of 18-55 with a BMI of more than 30 (http://www.nhlbisupport.com/bmi/) 

• Non-smokers

You will receive

• An 8-week supervised weight loss program

• Free meals during the intervention

• Assessment of cardiovascular fitness and cholesterol

• Body composition assessment

• Nutritional analysis

To volunteer, contact Kelli McCall at 720-848-6418 or kelli-mccall@ucdenver.edu. COMIRB No. 06-0383.

Overweight people with irritable bowel syndrome needed for study

(Feb. 6, 2009) Researchers are enrolling for a research study that examines the impact of a low-carbohydrate (Atkins) diet on Irritable Bowel Syndrome.

Participants must:

  1. be 18-70 years old, male or female
  2. have diarrhea-predominant Irritable Bowel Syndrome
  3. be overweight
  4. desire to use the Atkins Diet for possible weight loss
  5. be in stable health

Participants will be paid for completing the study and will receive all meals free for 6 weeks.

Contact Nicole Jacobson at Nicole.Jacobson@UCDenver.edu to learn more about the study and whether you might qualify.

COMIRB Study No. 07-0799. PI: Gregory Austin, MD

Prevention of Obesity in Women via Estradiol Regulation (POWER)

(Jan. 15, 2009) Healthy women between the age of 20-40 with regular menstrual cycles who are not using hormonal contraceptives for a study on the prevention of obesity.

Benefits for study volunteers include:

  1. Measurement of body composition and bone density
  2. Fitness testing
  3. Comprehensive diet analysis
  4. Personalized and supervised exercise program

Compensation will be provided for your time. Contact Ellie Gibbons at 720-848-6408 or Ellie.Gibbons@UCHSC.EDU. COMIRB protocol# 06-0512

Sedentary and diabetic men, women needed

(Jan. 15, 2009) Sedentary men and women aged 30-50 might be eligible to participate in a metabolism study investigating how fat stored in your muscle affects insulin activity.

In addition, women and men with Type II Diabetes aged 30-50 might be eligible to participate in this study as well.

Exclusions: You cannot participate if you: smoke, have hyperlipidemia, or have been told by your doctor not to exercise.

Two different preliminary assessments will measure:

  1. Body fat content Maximal exercise capacity (VO2max)
  2. Heart rhythm Resting metabolic rate
  3. Glucose tolerance
  4. Blood tests
  5. Health and physical examination performed by a physician

Volunteers will complete one metabolic study day following a 12 hour fast, where you will lie quietly for 4 hours, exercise for 1.5 hours at an easy to moderate intensity (45 percent of maximal capacity), and lie quietly again after exercise for 2 hours. All three visits will be performed at the General Clinical Research Center. Diet will be controlled for three days before each study day.

For the metabolic study day, the following will occur:

  1. Infusion of naturally occurring tracer of carbohydrate and fat through an intravenous catheter Blood sampling from a catheter placed in a hand vein 3 muscle biopsies
  2. 1.5 hours of exercise at 45 percent of maximal capacity

Compensation will be provided. P.I. Dr. Bryan Bergman, COMIRB # 03-398. Call Devon at 303-724-3968 for more information about this study.

Muscle signaling and estrogen

(Jan. 8, 2008) Healthy young women are needed to participate in a research study on Muscle Signaling and Estrogen (MUSE) to find out if the sex hormone estrogen helps protect against muscle loss when the muscle is not used.

Qualifications to volunteer:

  1. Healthy women between the age of 21-40 years
  2. Regular menstrual cycles
  3. No current use of hormonal contraceptives
  4. Physically active but not a competitive athlete
  5. Willing to wear a knee brace and use crutches for nine days

Benefits for study volunteers include:

  1. Measurement of body composition and bone density
  2. Fitness testing
  3. Compensation will be provided for your time

If interested contact Ellie Gibbons at 720-848-6408 or ellie.gibbons@uchsc.edu. Principle investigator: Catherine Jankowski, PhD. COMIRB No. 07-0379.

Weight gain in men

(Nov. 17, 2008) Male volunteers are needed for a research study on diet, physical activity and weight gain over time. (Eating Adaptations over Time Study).

Contact us if you are:

  1. Male & 25-35 years old
  2. Have at least one 1st degree relative who is overweight or obese
  3. Have dieted in the past but are currently weight stable
  4. Your Body Mass Index is between 23-30. You may check this at: http://nhlbisupport.com/bmi/. We especially need people with BMIs between 26-29

Receive at no cost:

  1. Dietary analysis
  2. Lab work
  3. Body fat measurement
  4. Measure of how many calories you use
  5. Monetary compensation for your time

Longitudinal Predictors of Weight Gain COMIRB 03-778. Principle investigator: Dan Bessesen, MD, contact: EATS Study EATS.study@uchsc.edu, 303-315-9089

 

Exercise motivation in women

(Oct. 1, 2008) female volunteers are needed for a research study that will look at what can make exercise feel more difficult to women with and without type 2 diabetes.

To qualify you must:

 ü    Be a woman between 50 and 70 years old

 ü    Be generally healthy with or without type 2 diabetes

 ü    Be a non-smoker

 ü    Have gone through menopause.

 ü    Currently exercise no more than once per week.

 ü    Have a Body Mass Index between 25 and 35 (Check your Body Mass Index at http://www.nhlbisupport.com/bmi/).

Financial compensation and free medical and exercise testing will be provided for qualified participants.

For Information call Leah at 303-724-2255. Principal Investigator: Amy Huebschmann, MD. COMIRB Protocol # 07-0849.

 

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