Cushing’s syndrome research
(August 26, 2008) Subjects are needed for an open label study of the efficacy and safety of Mifepristone in the treatment of the signs and symptoms of endogenous Cushing’s syndrome.
Participant requirements:
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men and women 18 years of age and older
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requiring medical treatment of hypercortisolemia
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having two of more of the signs/symptoms related to hypercorisolemia: Cushinoid appearance, increased body weight or central obesity, proximal muscle weakness, low bone mass, hirsutism and/or acne and/or violaceous striae
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female participants must be willing to have a serum pregnancy test as well as use a non-hormonally medically acceptable method of contraception during the study
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willing to attend 13 visits for study related materials over a 24-week period
Qualified participants will receive:
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DXA bone scan
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laboratory testing
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EKG’s
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financial compensation
For more information, contact Seismic Study line at 720-283-8280 or email Sylene.Johnson@uchsc.edu.
Principal investigator: Janice Kerr, MD; COMIRB #08-0347