Healthy children needed for measuring brain structure, function in autism
(Sept. 19, 2008) The Neuromagnetic Imaging Center at the University of Colorado is looking for healthy control subjects to participate in a brain imaging research study examining the relationship between brain structure and function in autism. Our team is studying the differences between people who have autism, parents of children with autism, and those with no history of a developmental disability. Brain structure and activity will be measured using magnetoencephalography (MEG) and magnetic resonance imaging (MRI).
Who is eligible to participate?
- Children (up to age 18) without autism or Asperger’s syndrome.
- Parents of children without autism or Asperger’s syndrome are also welcome.
Eligibility limitations:
- Participants must not have any permanent metal objects/implants in the body.
- Participants should not currently be abusing drugs or alcohol.
- Participants should be able to arrange for transportation to the 9th Avenue Campus of the University of Colorado Health Sciences Center.
Participants will:
- Be invited to the laboratory for a tour and orientation.
- Complete a series of psychological tests assessing memory, attention, and intellect. Participate in a magnetoencephalographic (MEG) recording: participants will lay on a bed and watch a movie while researchers record activity in the brain. Have a magnetic resonance image (MRI) taken to look at the anatomy of the brain.
- Be compensated for their time.
Information: Katie Youngpeter Katie.Youngpeter@ucdenver.edu. Principle investigate: Don Rojas, MD, COMIRB #07-0675
Children’s exercise and nutrition study
(July 11, 2008) Children are needed for a research study looking at the effect of exercise on food use by the body.
Caucasian and Hispanic children (average age 8-13 years old) are needed for a research study to look at the effect of a single exercise session on how the body handles a breakfast meal.
Screening assessments will include:
· a health and physical examination
· 2 blood draws; 2 hours between each blood draw
If you qualify to continue to participate in the study, based on the screening results, you will then complete the following tests over a two week period:
· measurement of your muscle and body fat content by DEXA
· ride a stationary bicycle 20-30 minutes with breath sampling
· measurement of how much energy your body uses when you are resting
You will then participate in the main part of the study. This requires you to do two test days separated by about 3-4 weeks. For three days before EACH of these test days, we will provide you with all your food and we will ask you not to play any sports or be very active. The night before each test day you will stay overnight in the Clinical Translational Research Center at The Children’s Hospital. Each of the test days will include the following.
· on one day, moderate bicycle exercise for 30 minutes and on the other day, 30 minutes of resting
· drawing of several blood samples from a small tube placed in a forearm vein
· breath sampling via a mouthpiece or plastic hood
Each test day will last approximately seven hours, and you will be asked to collect your urine while you are in the hospital.
Compensation will be provided upon the completion of these studies.
Contact Number: 303-315-0105
Principal Investigator Tracy Horton, PhD, Co-investigator and Contact: Teresa Sharp, PhD. COMIRB # 04-0940